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The most characterized lysosomal sorting pathway for GPCRs involves the ubiquitin-dependent endosomal-sorting complex required for transport machinery (ESCRT) (Bao et al., 2020)

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(iii) disruption of metabolic support of neurones and oligodendrocytes 147,148

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[DOI] [PMC free article] [PubMed] [Google Scholar] 367.Kapteijn R, Shitut S, Aschmann D, Zhang L, de Beer M, Daviran D, Roverts R, Akiva A, van Wezel GP, Kros A, Claessen D