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This highly reactive compound can cause lipid peroxidation and destabilization of cell membranes, DNA damage, and subsequent activation of the DNA repair enzyme poly (ADP-ribose) polymerase (PARP) leading to cellular energy collapse and death (48, 50)

B12 supports liver health through its role in methionine synthesis and the methylation cycle that the liver depends on for detoxification

The fat-fighting cocktail can strain your kidneys if you're not hydrating, leading to a stomach ache and potential urinary problems

Legality and Availability FDA Status : Not approved for human use in the US

Research has documented lower circulating MOTS-c in patients with obesity, type 2 diabetes, and insulin resistance, and higher levels in populations with healthy metabolic aging