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In an ischemic mouse model, lactate was shown to trigger astrogliosis through the activation of Akt and STAT3 signaling pathways, further linking metabolic shifts to astrocyte reactivity 78

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Botulinum toxin blocks mast cells and prevents rosacea like inflammation

A review of neuroprotection pharmacology and therapies in patients with acute traumatic brain injury

To help protect the antioxidant function of alpha-tocopherol (by preventing the formation of alpha-tocopherol radical) in foods and during digestion, some manufacturers have added compounds to this site of alpha-tocopherol through ester bonds

Thrombus formation and the subsequent activation of the coagulation cascade with final generation of fibrin is facilitated by the mCRP-mediated enhancement of tissue factor on the endothelial cell surface, platelet aggregation and thrombus growth (207, 208) (Figure 7)