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People with kidney failure receiving dialysis often have L-carnitine deficiency, leading to fatigue and muscle weakness L-carnitinealso known as levocarnitineis an amino acid that helps with weight loss, heart health, and brain function

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MS2 experiments were performed at a resolution of 17,500 with maximum IT of 100 ms for pVTA and 50 ms for catalase, and TopN was used for the 5 most abundant precursor ions per MS2

This work was supported by the Medicine Interdisciplinary Seed Fund (BMU20140435) by Health Science Center, Peking University

The lipid kinase, PI3K, is activated by the insulin receptor and it phosphorylates membrane localized phosphatidylinositol-4,5-bisphophate (PIP 2