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Consistent with OA progression features, the DMM group exhibited deteriorated subchondral bone microstructure compared to the sham group, characterized by reduced BV/TV and Tb.Th, along with increased Tb.N and Tb.Sp

doi: 10.2174/0929867328666211117094550

A single-blinded human trial assessing the combination of vitamin C (1 g) and vitamin E (400 mg) in healthy adults showed the combination of the two vitamins improved Interlukin-1 and tumor necrosis factor- (TNF-) levels and reduced lipopolysaccharide-induced prostaglandin E2 production, suggesting an enhanced immune response (50)

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ICAM-1, intercellular adhesion molecule 1

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