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Due to these confounding effects, precise model systems are needed to elucidate independent roles and reactions of VEGFR-2 in mechanosignaling

Wieseler J, Ellis AL, McFadden A, Brown K, Starnes C, Maier SF, et al

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But mechanisms don't always translate cleanly from bench to bedside

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The growth-promoting effects of GH and IGF-1 could theoretically accelerate malignant cell division
