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Carnitine is made in the body from the amino acids, lysine and methionine.* Carnitine is often called an amino acid because of its chemical makeup, however it is actually a vitamin-like nutrient, related in structure to the B vitamins.* It plays an essential role in transporting fatty acids into the muscles for energy, and is needed to transport these substances into the heart muscle.* Nearly 60% of the energy for the heart muscle is supplied by fatty acids.* It is also one of the two amino acids which promote sperm motility.*

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*Correspondence: Zhicheng Gong [email protected] Tang [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Nutrition and Metabolism, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

When CPT1C is upregulated, it increases FA consumption, and ATP production, facilitating tumor growth and survival 43