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To date about 100 distinct genes or loci associated with this heterogeneous disease are known [14]

Pekkinen J, Rosa-Sibakov N, Micard V, et al

Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analysis was conducted using the R ClusterProfiler package to investigate the roles of DEGs

Spermidine has also been shown to be associated with a delay is age-related cognitive decline

doi: 10.1002/smll.202203182 [DOI] [PubMed] [Google Scholar] 121.Long Q, Upadhya D, Hattiangady B, et al

Beyond metabolic benefits, recent studies also indicate that IF may moderate immune dysregulation by influencing critical inflammatory signaling pathways, which could have therapeutic implications for autoimmune diseases [59]