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Systemic NAC treatment resulted in substantial improvement of liver portal fibrosis, with a significant reduction in bile ducts surrounded by onion-skin-like fibrosis, and a significant reduction in collagen I/III stainings, indicating improvement in liver fibrosis (Fig

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Consequently, downregulation or knockdown of GR in prostate carcinoma cell lines led to the downregulation of LEDGF/p75 expression, reduced clonogenicity and tumoursphere formation as well as enhanced their sensitivity to docetaxel-induced tumour cell death [177]

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An internal standard (IS) solution, containing 13C isotope-labelled GSH and 13C isotope-labelled GSSG, was prepared in an antioxidation buffer

Hence, there is a need to investigate this matter in greater detail