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In stroke, particularly ischemic stroke, lipid metabolism exerts a dual role in neuroprotection and neurotoxicity by modulating inflammatory responses (Xu et al., 2021), immune cell activation, oxidative stress, and maintaining BBB integrity through phospholipid and sphingolipid pathways (Sun et al., 2016

Over a long term these effects increase the rate of carcinogenesis, cataract formation, cause embryo development issues as well as affect the overall life span of the organism

M.CoppiE.Padilha DalenogareD.TitizM.et al (2020)

The Bell scale score clearly depicts the opposing trend of the condition of participants with ME/CFS versus controls, with a smaller score reflecting the lower functional level of patients compared with a higher score of fully functional controls

Fedorovich SV, Waseem TV, Puchkova LV