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Additionally, ascites, anemia, abdominal pain, and neutropenia were observed in a phase III study of tivantinib (Rimassa et al., 2018)
Maintenance protocols work for ongoing optimization at lower cost

Epidermal growth factor receptor targeting in cancer: a review of trends and strategies
These pathways include carbon metabolism, glycolysis/gluconeogenesis and the biosynthesis of amino acids pathways (Figures 3I, J)

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