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Biochemical characterization of Pt GSTF8 To characterize the enzymatic function of arGSTs in the anthocyanin pathway in more detail, we decided to use the structure-elucidated Pt GSTF8 as a representative model enzyme in our biochemical assays

Ketamine is reported to produce mitochondrial dysfunction and oxidative stress that further lead to cause psychosis in mice [2]

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PRKN blocks SREBF2/ACAT2 signaling-mediated CC cell proliferation and immune evasion CCK8 and colony formation assays corroborated that PRKN overexpression inhibited CC cell proliferation, and the promoting effects of SREBF2 on CC cell proliferation were reversed by ACAT2 knockdown again (Fig

This and many other hitherto uncharacterised factors induce accumulation of pathogenic inclusions differently termed as Lewy bodies in neurons of PD patients (Marotta et al., 2021) or glial cytoplasmic inclusions in oligodendrocytes of Multiple System Atrophy (MSA) patients (Reddy and Dieriks, 2022)