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Description
( b ), Smurf1-HECT ( c ) or Smurf2 ( d )
The disulfiramethanol reaction

Animal studies have revealed embryofetal toxicity at supratherapeutic doses

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Infants, children, adolescents and women of reproductive age are also at high risk of deficiency in populations where dietary intake of B12-containing animal-derived foods is restricted

Clinical data suggest potential utility in managing conditions such as hepatitis B and HIV, and in contexts where an enhanced immune response is desirable