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The arcuate nucleus of the hypothalamus, and specifically, anorectic pro-opiomelanocortin (POMC), orexigenic neuropeptide Y (NYP), and agouti-related peptide neurons (AgRP) are key players in the regulation of appetite ( Figure 3 Additionally, disruption of CNS dopaminergic tone with relative dopamine deficiency may lead to hyperphagia

The concentration of Glutathione S Transferase mu can then be calculated by reading the O.D

*Correspondence: Jianzhou Ye, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

2024;203 doi: 10.1016/j.phrs.2024.107155

In summary, the accumulative data present in the human and animal models suggest that cessation of phallic growth is probably not caused by down regulation of the AR, nor by excess prepubertal androgens
