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Inflammatory Bowel Disease Inflammatory bowel disease (IBD) includes two chronic intestinal inflammatory conditions: Crohn's disease (CD) and ulcerative colitis (UC), characterized by an overactivation and dysregulation of the immune system with a relapsing-remitting pattern

We also recognize that the evidence is less conclusive for individuals with normal B12 levels

One of our impressive findings is that TRPM7 contributes to pyroptosis

The geroscience hypothesis proposes this principle but necessitates experimental testing

Researchers think this happens when organosulfur compounds and metabolites of said compounds interact with the central nervous and immune systems

Since it was first suggested that the symptoms of ME/CFS are secondary to acquired abnormalities in voltage-gated or ligand-gated ion channels [154, 155], growing evidence supports intracellular secondary messenger signalling and ion channel dysfunction in ME/CFS pathophysiology