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This can lead to several negative consequences, including: 1

If the current dose is well-tolerated and clinical goals are not yet met, the provider may advance per the label

Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: Etiologic and therapeutic concerns

Zebrafish-based screening of antiseizure plants used in traditional Chinese medicine: magnolia officinalis extract and its constituents magnolol and honokiol exhibit potent anticonvulsant activity in a therapy-resistant epilepsy model

doi: 10.1111/tpj.14855 117 ZaheerI

Therefore, the processes resulting in the increase of cellular labile iron, such as uptake transferrin [27, 28], inhibition of the ferroportin exporter [29] and degradation of ferritin [30, 31], will sensitize the cell to lipid peroxidation and eventual cell death