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Both drugs showed significant antitumor activity, with serum asparaginase activity (SAA) 0.1 UI/ml (considered therapeutic) in 95% of patients in both groups after 18 days of treatment and 25 days after treatment

Zhao HM, Xu R, Huang XY, Cheng SM, Huang MF, Yue HY, et al

Simultaneously, AT-I weakens NF-kB-mediated NLRP3 inflammasome formation, macrophage infiltration, and the expression levels of inflammatory cytokines such as TNF-, IL-6 and IL-1, thus suppressing hepatic inflammation and steatosis

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Symptoms of contact dermatitis include a red, elevated rash at the site of contact with the irritating substance

[DOI] [PubMed] [Google Scholar] 371.Deleskog A., Hilding A., Brismar K., Hamsten A., Efendic S., Ostenson C.G