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We next traced the metabolic flux of exogenous 3,3- 13 C 2 -cystine and found decreased intracellular 13 C-labeled GSH in GDIL knockown cells (Fig
[PubMed] [Google Scholar] Heyworth P
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Izumi, Y., & Kaji, R
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In terms of angiogenesis, lactate can enter vascular endothelial cells via MCT1, leading to IB phosphorylation and subsequent degradation, thereby activating the NF-B pathway and upregulating IL-8 transcription, a key mediator of angiogenesis
