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AOD9604 was originally developed after research on mice, but subsequent studies in human have shown no efficacy for the potential treatment of obesity.

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Studies indicate that NNMT inhibition by compounds such as 5-Amino-1MQ can result in reduced fat mass and improved insulin resistance

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No IGF-1 or glucose disruption: Unlike HGH, AOD-9604 does not significantly increase IGF-1 or negatively affect insulin sensitivity, making it a safer candidate for metabolic regulation