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These cases underline the potential neurotoxic effects of gadolinium, particularly when used intrathecally, and highlight the need for caution and further research into the safe use of magnetic resonance imaging contrast agents

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reference.medscape.com

This oxidative stress is not only involved in the toxicity of xenobiotics but also in the pathophysiology of various ailments like ischaemia reperfusion injury, vascular endothelium, deep injuries, organ dysfunction, shock, inflammation, sepsis, diabetic retinopathy, cancer, cognitive dysfunction, cataract, and heart disease

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