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Description
The polymeric nanoparticles were dual-surface tailored with two key features: (i) a brain-targeted acid-responsive angiopep-2 moiety that triggers a structural rearrangement within BBB endosomal vesicles, and (ii) an L-histidine moiety that provides preferential accumulation into GB cells after BBB crossing
The PCR products were gel-purified and subjected to bulk Sanger-sequencing
These mice develop steatohepatitis after eight months [95]
The import of cystine by xCT has been at the forefront of many cysteine metabolism studies in cancer cells as many cancers, including glioblastoma, triple-negative breast cancer, and non-small cell lung cancer, overexpress and use xCT for cystine uptake [22,26,27,28,29,34]
These numbers require context
Another study found no association, whether positive or negative, between rs9939609a and alcohol intake (112)
