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GST tagged fusion proteins bind to glutathione agarose and, after washing, are eluted with elution buffer with excess glutathione Protein refolding Reducing agents are common additions to protein purification buffers because they help keep many proteins from forming unnatural disulfide bonds and aggregating

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From a clinical perspective, prolactin is mainly of interest in patients with hyperprolactinemia causing infertility, amenorrhea, or in case of a mass effect produced by large prolactinomas pressing on the optic chiasm

Clinical trials investigating obesity used these dosing ranges with favorable safety outcomes

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