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IB analysis of Smurf1 and Smurf2 in HCT116 cells treated with indicated compounds (1 M, 12 h)

B 12 , 30493062 (2022)

doi: 168

The F1 generation demonstrates 45% sperm count reduction and 38% testosterone decrease, while the F2 generation exhibits persistent sperm motility and morphological abnormalities attributable to heritable DNA methylation changes
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Without clinical formulation, results are unpredictable

Otogawa K, Kinoshita K, Fujii H, Sakabe M, Shiga R, Nakatani K, et al
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