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Studied / plausible use-cases (stronger preclinical support): neuroprotection in ischemia models, neurotrophin modulation (e.g., BDNF), immune/inflammation gene expression changes in stroke models

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How TB-500 is thought to work The proposed mechanisms of TB-500 are still being investigated, and they should be described with appropriate hedging

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10.3390/pharmaceutics11110598 CrossRef Google Scholar View reference in article 77 LochheadJ