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Naito, Y., Uchiyama, K

Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor

Furthermore, co-administration of arginine with potassium-sparing diuretics (e.g., spironolactone, amiloride) is cautioned, as both can increase serum potassium levels and together may precipitate hyperkalemia (high potassium), which in turn may lead to dangerous heart arrhythmias

It influences energy metabolism by improving glucose homeostasis and insulin sensitivity and enhances glucose uptake and utilization in cells which leads to improved energy metabolism

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