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Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility In a 2-year dietary carcinogenicity study in mice, lomitapide was administered at doses of 0.3, 1.5, 7.5, 15, or 45 mg/kg/day

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HDLs anti-thrombotic effects are also mediated, in part, through HDLs ability to inhibit tissue factor and factors X, Va, and VIIIa (Figure 10) (832)
