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Ustekinumab was found to be well-tolerated by patients with UC, and the adverse event profile did not differ significantly from previously known medications

F.LeeJ.et al (2020)

Deficiencies are generally seen only after long antibiotic therapies which deplete the intestinal microbiota or following excessive consumption of raw eggs

Kobayashi M, Lee ES, Fukui Y
Zeiger E

CRBN (Cereblon) and DDB1 (DNA damage-binding protein 1) are proteins that play crucial roles in various cellular processes, including DNA repair, cell cycle regulation, and protein degradation
