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[DOI] [PubMed] [Google Scholar] 21.Yao JK, Leonard S, Reddy RD

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also observed similar phenomena in the testes of STZ-induced diabetic mice and HG-treated GC-1spg cells, and found that BRD7 inhibits Clusterin expression by regulating hypermethylation of the Clusterin promoter in an EZH2-dependent manner, thereby suppressing AMPK signaling to promote ferroptosis and induce DM-related testicular injury [178]