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13 In this review, we summarise the evidence related to the effects of GLP-1 RAs on these outcomes ( Figure 1 ), which may shed light on the potential of these agents to be used in the clinical care of HF patients and investigated in large clinical trials to evaluate clinical outcomes

Am J Physiol Endocrinol Metab 324: E449E460
Consequently, an effort has been made to review various plant-derived products possessing GLP-1 activating properties, specifically those acting as agonists on the GLP-1 receptor, which demonstrate interactions with both the catalytic site and the secondary binding site present in the GLP-1 receptor [8]

Effects of GLP-1 receptor agonists and SGLT-2 inhibitors on cardiac structure and function: a narrative review of clinical evidence

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