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Veljaca, Marija et al, The development of PL 14736 for treatment of inflammatory bowel disease, Advanced in GI pharmacology, 2002 O-32

Abstract Glucagon-like peptide 1 (GLP-1) is best known as an incretin hormone, secreted from L cells in the intestine in response to nutrient ingestion to stimulate glucose-dependent insulin secretion

Previous dieting attempts can further slow metabolism, while psychological fatigue and motivation dips make consistency harder

Mounjaro (tirzepatide) A once-weekly dual GLP-1/GIP receptor agonist

This compound patent should technically expire in March 2026, which is twenty years from when the patent was filed