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Improving health outcomes of people with diabetes: target setting for the WHO Global Diabetes Compact

2012;143(2):325327.e2

For some people, hunger increases gradually, while others notice a more noticeable change within the first month

[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Masclee G.M.C., Keszthelyi D., Conchillo J.M., Kruimel J.W., Bouvy N.D., Masclee A.A.M

This variability necessitates personalized treatment approaches, meticulous monitoring and managed expectations to optimize outcomes and ensure safety in real-world practice

Healthy storage of adipose tissue delays the progressive insulin resistance associated with obesity 74 , providing a plausible hypothesis that if GIPR agonism in adipose tissue can promote lipid storage in the correct location, this could result in positive effects on insulin sensitivity