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The phase 2 trial data shows that fatigue rates varied more by titration speed than by final dose

According to the American Diabetes Association, high blood glucose levels and being overweight translates to greater risk of developing complications

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Body Composition and Muscle Mass: Early data from the SURMOUNT-1 study using DXA scans showed that for the weight lost on Tirzepatide, approximately 75% was fat mass and 25% was lean mass

Despite producing more weight loss, tirzepatide had lower rates of treatment discontinuation due to gastrointestinal adverse events (2.7% vs 5.6% for semaglutide)

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