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Persistent or intense hunger could mean you are still on: A low starting dose Need more time for treatment Require a dose adjustment from your clinician Dose, Titration, and When a Higher Dose Might Help Providers start semaglutide slowly to limit side effects and then raise the dose over weeks

doi: 10.1016/j.biopha.2023.115032

Over time, poor eating habits and insufficient physical activity can make it hard for cortisol levels to decrease

Be aware that these carry a small risk of euglycaemic diabetic ketoacidosis DPP-4 inhibitors (e.g., sitagliptin, linagliptin), which are generally well tolerated but less effective for weight reduction Metformin , if not already prescribed, remains the first-line oral agent for type 2 diabetes, though it can also cause gastrointestinal upset Insulin therapy , which may be necessary if oral agents and GLP-1 agonists are not tolerated or insufficient, though this carries a risk of hypoglycaemia When discussing alternatives with your GP, consider bringing up: The severity and duration of your symptoms Any dietary or lifestyle modifications you have already tried Your treatment priorities (e.g., cardiovascular protection, convenience) Other medical conditions or medications that may influence treatment choice NICE guidance (NG28) recommends individualised treatment approaches for type 2 diabetes, taking into account patient preferences, comorbidities, and tolerability

Lahariya, C

If youre switching from another medication, consult your doctor about how to transition safely