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Animal studies in general also indicate that caffeine is neuroprotective

The stated rationale was safety concerns, though many clinicians and compounding pharmacy groups argued the agency overstepped, noting that no specific safety signal justified the restriction for most of the affected peptides

Current knowledge concerning optimum nutritional status of riboflavin, niacin and pyridoxine
: Therapeutic peptides: Current applications and future directions

doi: 10.1093/bioinformatics/bth349 23 RamrezFDndarFDiehlSGrningBAMankeT
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