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[6] [3] [10] A mild deficiency may not cause any discernible symptoms, but moderate deficiency can cause various symptoms, such as feeling tired, lightheadedness, headaches, cold intolerance, pale skin, sore tongue, upset stomach, loss of appetite, hair and skin color changes, numbness or tingling (pins and needles) of the fingers and toes, and tinnitus, and vision, cognitive or psychological problems

B12 also promotes healthy brain and nerve function, aids in fat metabolism, and helps prevent anemia-related exhaustion

10.1038/s41598-024-75476-0 26

(2016) Randomized, placebo-controlled trial of methyl B12 for children with autism

Post-transcriptional upregulation of GPx-1 Factors other than selenium also modulate GPx-1 expression by post-transcriptional mechanisms

It has been shown to help with food intolerances and gastritis , addressing digestive inflammation, including stomach ulcers , pancreatitis , as well as colitis , rectocolitis , and Crohn's disease