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Sands BE, Peyrin-Biroulet L, Loftus EV, Danese S, Colombel J-F, Trner M, Jonaitis L, et al

EdalatM.2002Multiple functions of glutathione transferase

Using a human intestinal epithelial platform with functional L-cells, researchers can now directly stimulate the epithelium and measure endogenous GLP-1 and other incretin secretion in a physiologically relevant context enabling mechanistic interrogation of secretion biology upstream of receptors